Leather and vinyl chairs are far easier to wipe clean with a mild detergent. If germs are a major concern, it is hard to beat the benefits of a smooth surface. Leather is more durable than vinyl but overall, they both work well. However, the downside is they tend to be more expensive and can be a little cold at first when you sit. Which is best for a particular individual is a judgement call based on personal preference.
MPN: AVE61507$112.72 / PK
MPN: MMM08405$32.73 / CT
MPN: PGC18842$6.51 / EA
MPN: ITD101522$25.12 / CT
MPN: NSN5552905$27.94 / BX
MPN: AVE05601$22.25 / EA
MPN: CYO542016007$5.54 / EA
MPN: EGO50062$8.74 / EA
MPN: PGC96595CT$35.56 / CT
MPN: SCCX12J8002PCT$196.51 / CT
MPN: GPC23304$54.24 / CT
MPN: EGO16736$19.39 / PR